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Vitamin B12 has a very low risk of toxicity, so there's really no upper limit to how much you can take without harm

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Although this is a necessary first step in biomedical development, it is also a sign that R&D for these conditions operates in a somewhat rigged race, starting off with and slowed down by a lack of funding and available medical knowledge from the outset

Dihexa contains both polar amide and hydroxyl groups as well as extended hydrophobic aliphatic chains